TiumBio's Partner Hansoh Pharma Expands Indications for Merigolix (HS-10518) with Initiation of ART (Assisted Reproductive Technology) Development - Thailand PR News - [Banking](https://thailandbusinessnews.net/category/banking/) - [Companies](https://thailandbusinessnews.net/category/companies/) - [Economy](https://thailandbusinessnews.net/category/economy/) - [Press Releases](https://thailandbusinessnews.net/category/press-release/) - [PR Newswire](https://thailandbusinessnews.net/pr-newswire-updates/) - [Tech](https://thailandbusinessnews.net/category/tech/) - [Tourism](https://thailandbusinessnews.net/category/tourism/) - [Press Release](https://thailandbusinessnews.net/category/press-release/) - [Tech](https://thailandbusinessnews.net/category/tech/) # TiumBio's Partner Hansoh Pharma Expands Indications for Merigolix (HS-10518) with Initiation of ART (Assisted Reproductive Technology) Development ##### Up next ###### [RSQUARE Analytics: The Digital Lighthouse for Korean Real Estate Market That Global Investors Are Watching](https://thailandbusinessnews.net/press-release/rsquare-analytics-the-digital-lighthouse-for-korean-real-estate-market-that-global-investors-are-watching/) Published on 20 March 2025 ##### Author ##### [ CISION PRNewswire ](https://thailandbusinessnews.net/author/cision/) ##### Tags - [PRNewswire](https://thailandbusinessnews.net/tag/prnewswire/) ![](https://mma.prnasia.com/media2/2308813/tiumbio_logo_horizontal_c__7_Logo.jpg?p=medium600 "logo") Clinical Trial Approval of merigolix (TU2670, HS-10518) for the inhibition of premature LH (luteinizing hormone) surges in women undergoing COS (controlled ovarian stimulation) in China SEONGNAM, South Korea, March 20, 2025 /PRNewswire/ — TiumBio (KOSDAQ: 321550), a clinical-stage biopharmaceutical company focused on discovering and developing innovative therapeutics for patients with rare and incurable disease, announced today that its partner, Hansoh Pharma, has expanded the clinical indications of merigolix (Hansoh’s code: HS-10518), an oral gonadotropin-releasing hormone receptor antagonist. Hansoh Pharma recently received approval for an IND (Investigational New Drug) application targeting ART, expanding the development area of merigolix. COS has been an integral part of ART treatment cycles. Availability of different gonadotropins for ovarian stimulation and gonadotropin releasing hormone (GnRH) analogues for prevention of premature rise of LH during follicular phase offer an opportunity for a successful outcome in women with different subsets of ovarian response. Orally administered merigolix may be important in the control of premature endogenous LH surge and in reducing the cycle cancellation rate, with an improvement of pregnancy rate per cycle. Currently, in COS regimens, gonadotropin-releasing hormone (GnRH) products are only available in injectable form, which caused the pain and relatively high cost. "Hansoh Pharma’s selection of ART as a new indication is significant," said Hun-Taek Kim, Ph.D., MBA, CEO of TiumBio. "Compared to other indications, ART requires a shorter treatment period, which will enable faster development," he added. Meanwhile, merigolix is an oral GnRH receptor antagonist being developed for the treatment of endometriosis, uterine fibroids, and ART. TiumBio entered into a licensing agreement with Hansoh Pharma for merigolix for up to $170M plus tiered royalties upon net sales. Under the terms of the agreement, Hansoh Pharma obtained exclusive rights to develop and commercialize merigolix in Greater China. About TiumBio Co., Ltd. TiumBio (Kosdaq: 321550) is a clinical-stage biopharmaceutical company focused on the discovery and development of innovative therapeutics for patients with rare and incurable diseases. Its mission is to expand the hope and happiness of mankind through our science. TiumBio boasts three leading pipeline assets: merigolix (code name: TU2670), TU2218, and TU7710, all in various stages of clinical development. Merigolix is a once-daily, oral GnRH receptor antagonist being developed for the treatment of endometriosis, uterine fibroids, and assisted reproductive technology. TU2218 is a first-in-class oral immune-oncology therapy targeting TGF-β and VEGF pathways to promote response rates in cancer patients when used in combination with immune checkpoint inhibitors. TU7710 is a novel rFVIIa designed to extend its half-life in order to provide more clinical benefits to hemophilia patients with inhibitors. With its expertise in drug development, TiumBio is committed to the discovery and development of innovative treatments to ease the burden of debilitating diseases. For further information, visit our website at [www.tiumbio.com/en](http://www.tiumbio.com/en) and connect with us on [LinkedIn](http://www.linkedin.com/company/tiumbio). Contacts:Junseok Jang, Head of Corporate Communications & Investor RelationsDa-ye Song, Manager, Corporate Communications & Investor Relations [Source link ](https://www.prnasia.com/story/archive/4645687_CN45687_0?rand=89749) ``` This content was prepared by our news partner, Cision PR Newswire. 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